Total phenolic and flavonoid content, antioxidant effects and antidiarrheal activity of balacaturbhadrika churna - an ayurvedic preparation

Rahul Pratap, Hn N. Aswatha Ram, K. S. Chandrashekar, Vasudev Pai, Saleemulla Khan, Venkatesh Kamath

Research output: Contribution to journalArticle

Abstract

Balacaturbhadrika churna (BC) is an important pediatric preparation in Ayurveda. It is used to treat various diseases of gastro-intestinal tract particularly diarrhea in children. Free radicals cause oxidative damage in the intestine and are correlated with its diseases. In the current study, total phenolic and flavonoid contents of BC extracts were determined and their antioxidant evaluation in various in vitro models was carried out. Procedures mentioned in The Ayurvedic Formulary of India were followed to prepare in-house BC; alcoholic (BCAL) and aqueous (BCAQ) extracts were prepared and tested by standard procedures. BCAL was tested for antidiarrheal activity in castor oil induced model. The ethanolic extract showed better antioxidant activity in many of the models as compared to aqueous extract. The present study showed substantial amounts of flavonoids and phenolics in churna extracts. BCAL showed significant antidiarrheal activity against the tested model. The potential antioxidant and antidiarrheal activities displayed by Balacaturbhadrika churna extracts could be attributed to these contents.

Original languageEnglish
Pages (from-to)485-492
Number of pages8
JournalIndian Journal of Traditional Knowledge
Volume18
Issue number3
Publication statusPublished - 01-07-2019

Fingerprint

Antidiarrheals
Flavonoids
Antioxidants
Castor Oil
Formularies
Intestinal Diseases
Free Radicals
Intestines
India
Diarrhea
Pediatrics

All Science Journal Classification (ASJC) codes

  • Complementary and Manual Therapy
  • Complementary and alternative medicine

Cite this

@article{7bc067caa4014944a063634c47c9266d,
title = "Total phenolic and flavonoid content, antioxidant effects and antidiarrheal activity of balacaturbhadrika churna - an ayurvedic preparation",
abstract = "Balacaturbhadrika churna (BC) is an important pediatric preparation in Ayurveda. It is used to treat various diseases of gastro-intestinal tract particularly diarrhea in children. Free radicals cause oxidative damage in the intestine and are correlated with its diseases. In the current study, total phenolic and flavonoid contents of BC extracts were determined and their antioxidant evaluation in various in vitro models was carried out. Procedures mentioned in The Ayurvedic Formulary of India were followed to prepare in-house BC; alcoholic (BCAL) and aqueous (BCAQ) extracts were prepared and tested by standard procedures. BCAL was tested for antidiarrheal activity in castor oil induced model. The ethanolic extract showed better antioxidant activity in many of the models as compared to aqueous extract. The present study showed substantial amounts of flavonoids and phenolics in churna extracts. BCAL showed significant antidiarrheal activity against the tested model. The potential antioxidant and antidiarrheal activities displayed by Balacaturbhadrika churna extracts could be attributed to these contents.",
author = "Rahul Pratap and {Aswatha Ram}, {Hn N.} and Chandrashekar, {K. S.} and Vasudev Pai and Saleemulla Khan and Venkatesh Kamath",
year = "2019",
month = "7",
day = "1",
language = "English",
volume = "18",
pages = "485--492",
journal = "Indian Journal of Traditional Knowledge",
issn = "0972-5938",
publisher = "National Institute of Science Communication and Information Resources (NISCAIR)",
number = "3",

}

Total phenolic and flavonoid content, antioxidant effects and antidiarrheal activity of balacaturbhadrika churna - an ayurvedic preparation. / Pratap, Rahul; Aswatha Ram, Hn N.; Chandrashekar, K. S.; Pai, Vasudev; Khan, Saleemulla; Kamath, Venkatesh.

In: Indian Journal of Traditional Knowledge, Vol. 18, No. 3, 01.07.2019, p. 485-492.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Total phenolic and flavonoid content, antioxidant effects and antidiarrheal activity of balacaturbhadrika churna - an ayurvedic preparation

AU - Pratap, Rahul

AU - Aswatha Ram, Hn N.

AU - Chandrashekar, K. S.

AU - Pai, Vasudev

AU - Khan, Saleemulla

AU - Kamath, Venkatesh

PY - 2019/7/1

Y1 - 2019/7/1

N2 - Balacaturbhadrika churna (BC) is an important pediatric preparation in Ayurveda. It is used to treat various diseases of gastro-intestinal tract particularly diarrhea in children. Free radicals cause oxidative damage in the intestine and are correlated with its diseases. In the current study, total phenolic and flavonoid contents of BC extracts were determined and their antioxidant evaluation in various in vitro models was carried out. Procedures mentioned in The Ayurvedic Formulary of India were followed to prepare in-house BC; alcoholic (BCAL) and aqueous (BCAQ) extracts were prepared and tested by standard procedures. BCAL was tested for antidiarrheal activity in castor oil induced model. The ethanolic extract showed better antioxidant activity in many of the models as compared to aqueous extract. The present study showed substantial amounts of flavonoids and phenolics in churna extracts. BCAL showed significant antidiarrheal activity against the tested model. The potential antioxidant and antidiarrheal activities displayed by Balacaturbhadrika churna extracts could be attributed to these contents.

AB - Balacaturbhadrika churna (BC) is an important pediatric preparation in Ayurveda. It is used to treat various diseases of gastro-intestinal tract particularly diarrhea in children. Free radicals cause oxidative damage in the intestine and are correlated with its diseases. In the current study, total phenolic and flavonoid contents of BC extracts were determined and their antioxidant evaluation in various in vitro models was carried out. Procedures mentioned in The Ayurvedic Formulary of India were followed to prepare in-house BC; alcoholic (BCAL) and aqueous (BCAQ) extracts were prepared and tested by standard procedures. BCAL was tested for antidiarrheal activity in castor oil induced model. The ethanolic extract showed better antioxidant activity in many of the models as compared to aqueous extract. The present study showed substantial amounts of flavonoids and phenolics in churna extracts. BCAL showed significant antidiarrheal activity against the tested model. The potential antioxidant and antidiarrheal activities displayed by Balacaturbhadrika churna extracts could be attributed to these contents.

UR - http://www.scopus.com/inward/record.url?scp=85071388474&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85071388474&partnerID=8YFLogxK

M3 - Article

VL - 18

SP - 485

EP - 492

JO - Indian Journal of Traditional Knowledge

JF - Indian Journal of Traditional Knowledge

SN - 0972-5938

IS - 3

ER -