Toxic epidermal necrolysis and agranulocytosis: Rare adverse effects of ciprofloxacin

Gatha M. Upadya, K. Ruxana

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Ciprofloxacin is one of the most commonly used antibacterial agents with relatively few side effects. Serious adverse reactions reported with ciprofloxacin are rare with an incidence of 0.6%. Recently we came across two rare adverse effects of ciprofloxacin, viz. toxic epidermal necrolysis and agranulocytosis. To our knowledge, a total of seven cases have been reported in the literature documenting an association between oral ciprofloxacin administration and toxic epidermal necrolysis. One case of granulocytopenia, four of pancytopenia and fifteen of leucopenia worldwide have been reported. With the use of ciprofloxacin becoming more and more widespread, these two rare but fatal complications of ciprofloxacin should be borne in mind.

Original languageEnglish
Pages (from-to)461-463
Number of pages3
JournalIndian Journal of Medical Sciences
Volume63
Issue number10
DOIs
Publication statusPublished - 01-10-2009

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Stevens-Johnson Syndrome
Agranulocytosis
Ciprofloxacin
Pancytopenia
Leukopenia
Oral Administration
Anti-Bacterial Agents
Incidence

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

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Toxic epidermal necrolysis and agranulocytosis : Rare adverse effects of ciprofloxacin. / Upadya, Gatha M.; Ruxana, K.

In: Indian Journal of Medical Sciences, Vol. 63, No. 10, 01.10.2009, p. 461-463.

Research output: Contribution to journalArticle

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