Trend in seroprevalence of Hepatitis B virus infection among blood donors of coastal Karnataka, India

Karandeep Singh, Sudha Bhat, Shamee Shastry

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Background: Hepatitis B is one of the transfusion transmissible infections. The prevalence of this infection varies across the different geographies. Noting the trend in seroprevalence is useful to assist the preventive strategies. The aim of this study was to determine the trend of seroprevalence of hepatits B in costal Karnataka over a three-year period. Methodology: The study was conducted at the blood bank of a tertiary care hospital serving predominantly the people of coastal Karnataka. A retrospective analysis of blood donors over a period of three years was done to assess the seroprevalence and the trend of hepatitis B infection. ELISA was used to detect the hepatitis B surface antigen in the donors as a marker of infection. Results: A total of 30,428 blood donors were studied. 189 (0.62%) were positive, which comes under the "low prevalence (< 2%) zone" per World Health Organization (WHO) guidelines. A decreasing trend over three years was seen. Replacement donors and male blood donors showed higher seropositivity compared to voluntary donors and female donors. Chi-square test was used to calculate the significance of difference between the groups. Conclusion: Coastal Karnataka has a low prevalence of hepatitis B in blood donors with a decreasing trend over the last three-year period.

Original languageEnglish
Pages (from-to)376-379
Number of pages4
JournalJournal of Infection in Developing Countries
Volume3
Issue number5
Publication statusPublished - 06-08-2009

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Seroepidemiologic Studies
Virus Diseases
Blood Donors
Hepatitis B virus
India
Hepatitis B
Tissue Donors
Infection
Blood Banks
Geography
Tertiary Healthcare
Chi-Square Distribution
Hepatitis B Surface Antigens
Tertiary Care Centers
Enzyme-Linked Immunosorbent Assay
Guidelines

All Science Journal Classification (ASJC) codes

  • Parasitology
  • Microbiology
  • Infectious Diseases
  • Virology

Cite this

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abstract = "Background: Hepatitis B is one of the transfusion transmissible infections. The prevalence of this infection varies across the different geographies. Noting the trend in seroprevalence is useful to assist the preventive strategies. The aim of this study was to determine the trend of seroprevalence of hepatits B in costal Karnataka over a three-year period. Methodology: The study was conducted at the blood bank of a tertiary care hospital serving predominantly the people of coastal Karnataka. A retrospective analysis of blood donors over a period of three years was done to assess the seroprevalence and the trend of hepatitis B infection. ELISA was used to detect the hepatitis B surface antigen in the donors as a marker of infection. Results: A total of 30,428 blood donors were studied. 189 (0.62{\%}) were positive, which comes under the {"}low prevalence (< 2{\%}) zone{"} per World Health Organization (WHO) guidelines. A decreasing trend over three years was seen. Replacement donors and male blood donors showed higher seropositivity compared to voluntary donors and female donors. Chi-square test was used to calculate the significance of difference between the groups. Conclusion: Coastal Karnataka has a low prevalence of hepatitis B in blood donors with a decreasing trend over the last three-year period.",
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Trend in seroprevalence of Hepatitis B virus infection among blood donors of coastal Karnataka, India. / Singh, Karandeep; Bhat, Sudha; Shastry, Shamee.

In: Journal of Infection in Developing Countries, Vol. 3, No. 5, 06.08.2009, p. 376-379.

Research output: Contribution to journalArticle

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