Abstract

Objective: To determine the trends in prescribing antidiabetic drugs among patients with type 2 diabetes mellitus (DM) over a period of three years Methods: The study was conducted as a cross sectional observational study. Prescription pattern of diabetic patients who admitted during 2008 to 2010 in medicine wards was collected from tertiary care hospital in south India. And analysed using SPSS version 20. Results: As per the study criteria, data were collected from 773, 700 and 647 type 2 diabetes mellitus patients who were admitted during the years 2008, 2009 and 2010 respectively in the medicine wards. The study showed that most of the patients were males. The mean age of the study population was 57.8 years. Type 2 DM patients had a prevalence of microvascular complications from 8-18.14% and macro vascular complications from 7.6-11.8% of the diabetic population over a period of three years. On evaluation of trends in prescribing for patients with type 2 DM over a period of three years, in monotherapy, there is a decrease in rate of prescription in 2009, but again it increased in 2010(p=0.020). Monotherapy was the predominant way of management with insulin followed by sulfonylureas and metformin. Combinations of sulphanylureas and metformin commonly used as dual therapy. Insulin, Sulphanylureas and metformin combination are commonly used as triple drug therapy. There is no difference in rate of prescription in dual therapy (p=0.419) and also three drug combinations (p=0.361) over a period of three years. And few cases four and five drug combinations were used. Conclusion: We observed there is no changes in trends in prescribing antidiabetic drugs over a period of three years and also shows physicians are adhering to standard guidelines for diabetic treatment in this hospital.

Original languageEnglish
Pages (from-to)12994-13007
Number of pages14
JournalInternational Journal of Pharmacy and Technology
Volume8
Issue number2
Publication statusPublished - 01-06-2016

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Tertiary Healthcare
Medical problems
Hypoglycemic Agents
Tertiary Care Centers
Type 2 Diabetes Mellitus
Metformin
Insulin
Medicine
Prescriptions
Drug Combinations
Drug therapy
Macros
Population
Observational Studies
Blood Vessels
India
Therapeutics
Cross-Sectional Studies
Guidelines
Physicians

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

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title = "Trends in prescribing antidiabetic drugs over a period of three years in South Indian tertiary care hospital",
abstract = "Objective: To determine the trends in prescribing antidiabetic drugs among patients with type 2 diabetes mellitus (DM) over a period of three years Methods: The study was conducted as a cross sectional observational study. Prescription pattern of diabetic patients who admitted during 2008 to 2010 in medicine wards was collected from tertiary care hospital in south India. And analysed using SPSS version 20. Results: As per the study criteria, data were collected from 773, 700 and 647 type 2 diabetes mellitus patients who were admitted during the years 2008, 2009 and 2010 respectively in the medicine wards. The study showed that most of the patients were males. The mean age of the study population was 57.8 years. Type 2 DM patients had a prevalence of microvascular complications from 8-18.14{\%} and macro vascular complications from 7.6-11.8{\%} of the diabetic population over a period of three years. On evaluation of trends in prescribing for patients with type 2 DM over a period of three years, in monotherapy, there is a decrease in rate of prescription in 2009, but again it increased in 2010(p=0.020). Monotherapy was the predominant way of management with insulin followed by sulfonylureas and metformin. Combinations of sulphanylureas and metformin commonly used as dual therapy. Insulin, Sulphanylureas and metformin combination are commonly used as triple drug therapy. There is no difference in rate of prescription in dual therapy (p=0.419) and also three drug combinations (p=0.361) over a period of three years. And few cases four and five drug combinations were used. Conclusion: We observed there is no changes in trends in prescribing antidiabetic drugs over a period of three years and also shows physicians are adhering to standard guidelines for diabetic treatment in this hospital.",
author = "Acharya, {Leelavathi D.} and Rau, {N. R.} and N. Udupa and {Surulevel Rajan}, M. and K. Vijayanarayan",
year = "2016",
month = "6",
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pages = "12994--13007",
journal = "International Journal of Pharmacy and Technology",
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TY - JOUR

T1 - Trends in prescribing antidiabetic drugs over a period of three years in South Indian tertiary care hospital

AU - Acharya, Leelavathi D.

AU - Rau, N. R.

AU - Udupa, N.

AU - Surulevel Rajan, M.

AU - Vijayanarayan, K.

PY - 2016/6/1

Y1 - 2016/6/1

N2 - Objective: To determine the trends in prescribing antidiabetic drugs among patients with type 2 diabetes mellitus (DM) over a period of three years Methods: The study was conducted as a cross sectional observational study. Prescription pattern of diabetic patients who admitted during 2008 to 2010 in medicine wards was collected from tertiary care hospital in south India. And analysed using SPSS version 20. Results: As per the study criteria, data were collected from 773, 700 and 647 type 2 diabetes mellitus patients who were admitted during the years 2008, 2009 and 2010 respectively in the medicine wards. The study showed that most of the patients were males. The mean age of the study population was 57.8 years. Type 2 DM patients had a prevalence of microvascular complications from 8-18.14% and macro vascular complications from 7.6-11.8% of the diabetic population over a period of three years. On evaluation of trends in prescribing for patients with type 2 DM over a period of three years, in monotherapy, there is a decrease in rate of prescription in 2009, but again it increased in 2010(p=0.020). Monotherapy was the predominant way of management with insulin followed by sulfonylureas and metformin. Combinations of sulphanylureas and metformin commonly used as dual therapy. Insulin, Sulphanylureas and metformin combination are commonly used as triple drug therapy. There is no difference in rate of prescription in dual therapy (p=0.419) and also three drug combinations (p=0.361) over a period of three years. And few cases four and five drug combinations were used. Conclusion: We observed there is no changes in trends in prescribing antidiabetic drugs over a period of three years and also shows physicians are adhering to standard guidelines for diabetic treatment in this hospital.

AB - Objective: To determine the trends in prescribing antidiabetic drugs among patients with type 2 diabetes mellitus (DM) over a period of three years Methods: The study was conducted as a cross sectional observational study. Prescription pattern of diabetic patients who admitted during 2008 to 2010 in medicine wards was collected from tertiary care hospital in south India. And analysed using SPSS version 20. Results: As per the study criteria, data were collected from 773, 700 and 647 type 2 diabetes mellitus patients who were admitted during the years 2008, 2009 and 2010 respectively in the medicine wards. The study showed that most of the patients were males. The mean age of the study population was 57.8 years. Type 2 DM patients had a prevalence of microvascular complications from 8-18.14% and macro vascular complications from 7.6-11.8% of the diabetic population over a period of three years. On evaluation of trends in prescribing for patients with type 2 DM over a period of three years, in monotherapy, there is a decrease in rate of prescription in 2009, but again it increased in 2010(p=0.020). Monotherapy was the predominant way of management with insulin followed by sulfonylureas and metformin. Combinations of sulphanylureas and metformin commonly used as dual therapy. Insulin, Sulphanylureas and metformin combination are commonly used as triple drug therapy. There is no difference in rate of prescription in dual therapy (p=0.419) and also three drug combinations (p=0.361) over a period of three years. And few cases four and five drug combinations were used. Conclusion: We observed there is no changes in trends in prescribing antidiabetic drugs over a period of three years and also shows physicians are adhering to standard guidelines for diabetic treatment in this hospital.

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