Uncommon sites affected by a common disease: An autopsy study

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Abstract

Context: Disseminated tuberculosis (DTB) is quite an uncommon entity. It is usually undetected as it can present in an atypically bland manner and go unsuspected. Aims: Our study aimed to determine the frequency of DTB in autopsies in our setting. Subjects and Methods: A retrospective study was done for a period of 6 years, i.e., from January 2009 to December 2015, wherein all the cases of DTB encountered in autopsy specimens were included in the study. Results: During the study period, we encountered 19 cases of DTB. In all 19 cases, the organs examined were lung (19/19 cases), liver (18/19 cases), kidney (12/19 cases), spleen (18/19 cases), pancreas (3/19 cases), heart (8/19 cases), and brain (5/19 cases). Caseating epithelioid granulomas were seen in all cases of lungs (19/19 cases), 16 cases in liver, 12 cases in kidney, and 17 cases in spleen, 2 cases of heart, and 2 cases of pancreas. DTB accounted for 1.3% (n = 19) of all autopsy cases, with the mean age being 41.35 years. The male: female ratio was 18:1. Eleven out of 19 cases were unknown bodies. Acid-fast bacilli stain showed positivity in 10 cases. Conclusions: Despite recent technological advances in the diagnosis of tuberculosis, autopsy still remains an important complementary tool for identification of DTB.

Original languageEnglish
Pages (from-to)130-132
Number of pages3
JournalAnnals of Tropical Medicine and Public Health
Volume11
Issue number4
DOIs
Publication statusPublished - 01-07-2018

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All Science Journal Classification (ASJC) codes

  • Public Health, Environmental and Occupational Health

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