Unusual presentation of scleroderma

Research output: Contribution to journalArticle

Abstract

Scleroderma is a group of rare and complex diseases with varied clinical manifestations. The most obvious manifestation of the diseases is skin hardening and sclerosis. A 39-year-old woman presented with complaints of swelling of bilateral lower limbs. The patient also complained of spotty pigmentation of chest, back, and forearm. The patient gave history of weakness of left leg since 3 months. Antinuclear antibody (ANA), anticentromere, and antiDs DNA antibodies were negative. Clinical manifestations were unusual, as the patient had only edema and skin rashes. Visceral organ involvement was only in the form of abnormal liver function test especially lactate dehydrogenase (LDH). The patient also had grossly elevated creatine phosphokinase (CPK) suggesting muscle involvement, though symptom of muscle weakness was only mild. The patient was negative for antinuclear as well as anticentromere antibodies. Diagnosis in this patient was mainly based on skin biopsy findings.

Original languageEnglish
Pages (from-to)26-28
Number of pages3
JournalAnnals of Tropical Medicine and Public Health
Volume2
Issue number1
Publication statusPublished - 01-01-2009

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Antinuclear Antibodies
Liver Function Tests
Muscle Weakness
Pigmentation
Sclerosis
Creatine Kinase
Rare Diseases
Exanthema
L-Lactate Dehydrogenase
Skin Diseases
Forearm
Lower Extremity
Edema
Leg
Thorax
Biopsy
Muscles
Skin
Antibodies
DNA

All Science Journal Classification (ASJC) codes

  • Medicine(all)
  • Public Health, Environmental and Occupational Health

Cite this

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Unusual presentation of scleroderma. / Chowta, Nithyananda K.; Chowta, Mukta N.

In: Annals of Tropical Medicine and Public Health, Vol. 2, No. 1, 01.01.2009, p. 26-28.

Research output: Contribution to journalArticle

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