Urinary peptide levels in patients with chronic renal failure

Mungli Prakash, Nagaraj M. Phani, R. Kavya, M. Supriya

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Abstract

Introduction: Peptide levels in urine are found to be decreased in renal failure. In the current study urinary peptide levels were determined in chronic renal failure (CRF) patients. Method: 86 CRF patients and 80 healthy controls were selected for the study. Urinary proteins and peptide levels were determined by spectrophotometer based Lowry and Bradford methods. Urinary creatinine levels were determined by clinical chemistry analyzer. Results: There was significant decrease in urinary peptide levels in CRF patients and Urinary % peptides were significantly decreased in CRF patients as compared to healthy controls. Urinary % peptides correlated negatively with proteinuria. Conclusion: we have found decrease in urinary peptides and % urinary peptides in CRF patients and possibly measurement of % urinary peptides may possibly serve as better indicator in early detection of impairment in renal function.

Original languageEnglish
Pages (from-to)1-3
Number of pages3
JournalOnline Journal of Health and Allied Sciences
Volume9
Issue number3
Publication statusPublished - 01-07-2010
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Prakash, M., Phani, N. M., Kavya, R., & Supriya, M. (2010). Urinary peptide levels in patients with chronic renal failure. Online Journal of Health and Allied Sciences, 9(3), 1-3.