Uterine malignant mixed müllerian tumor camouflaging as pelvic sarcoma

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Malignant mixed Müllerian tumors (MMMTs) of the uterus are rare, aggressive tumors that present at an advanced stage and are associated with poor prognosis. They arise as a result of divergent carcinomatous and mesenchymal differentiation of tumor stem cells. Rarely one of the components may predominate contributing to diagnostic confusion. We present a rare case of uterine MMMT arising in endometrial adenocarcinoma, camouflaging as pelvic sarcoma with a major sarcomatous component. This case report highlights the importance of thorough tissue sampling and the role of immunohistochemistry (IHC) in arriving at an accurate diagnosis. This case also demonstrates the conversion theory of histogenesis of MMMTs.

Original languageEnglish
Pages (from-to)997-999
Number of pages3
JournalJournal of Cancer Research and Therapeutics
Volume11
Issue number4
DOIs
Publication statusPublished - 01-10-2015

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Malignant Mixed Tumor
Sarcoma
Neoplastic Stem Cells
Uterus
Neoplasms
Adenocarcinoma
Immunohistochemistry

All Science Journal Classification (ASJC) codes

  • Oncology
  • Radiology Nuclear Medicine and imaging

Cite this

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abstract = "Malignant mixed M{\"u}llerian tumors (MMMTs) of the uterus are rare, aggressive tumors that present at an advanced stage and are associated with poor prognosis. They arise as a result of divergent carcinomatous and mesenchymal differentiation of tumor stem cells. Rarely one of the components may predominate contributing to diagnostic confusion. We present a rare case of uterine MMMT arising in endometrial adenocarcinoma, camouflaging as pelvic sarcoma with a major sarcomatous component. This case report highlights the importance of thorough tissue sampling and the role of immunohistochemistry (IHC) in arriving at an accurate diagnosis. This case also demonstrates the conversion theory of histogenesis of MMMTs.",
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Uterine malignant mixed müllerian tumor camouflaging as pelvic sarcoma. / Monappa, Vidya; Kudva, Ranjini; Hasan, Roumina.

In: Journal of Cancer Research and Therapeutics, Vol. 11, No. 4, 01.10.2015, p. 997-999.

Research output: Contribution to journalArticle

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