Utilization pattern of anti-diabetic drugs in type 2 diabetes mellitus in tertiary care hospital

Merry Raphael, K. Vijayanarayana, Girish Thunga, N. Karthik Rao, N. Sreedharan

Research output: Contribution to journalArticle

Abstract

Background: Diabetes mellitus is a major public-health related problem. The increase in prevalence rates has led to an increase in the economic burden, worldwide. To manage the disease in a better way, Drug utilization research can be used as a strategy to justify the drug therapy. Aims: To study the drug prescribing pattern of anti-diabetic drugs in newly diagnosed type 2 DM patients. Materials and methods: A retrospective observational study was carried out in a tertiary care hospital. As per the study criteria, data was collected from medical records department (MRD) registry using ICD code E 11.9.Data was analysed using SPSS 20.0 and the DDD per 100 bed-days was calculated. Results: A total of 662 patients were newly diagnosed with type 2 DM. The mean age of study population was 52.5 ± 12.5 years and 427(64.5%) patients were male. Hypertension was the most common comorbidity observed in 189 (28.5%) patients. Among the anti-diabetic drugs, the utilization of insulin (0.088 DDDs per 100 bed-days in 2013 and 0.16 DDDs per 100 bed-days in 2014) was highest and among the oral anti-diabetic drugs the utilization pattern of metformin (0.058 DDDs per 100 bed-days in 2013 and 0.071 DDDs per 100 bed-days in 2014) was the highest in both 2013 and 2014. Conclusion: Biguanides (metformin) was highly prescribed anti -diabetic drug in both single and combination drug therapies. This study shows that the treatment pattern of type 2 DM patients is in accordance to the NICE (National Institute for Health and Clinical Excellence) guidelines.

Original languageEnglish
Pages (from-to)2063-2068
Number of pages6
JournalResearch Journal of Pharmacy and Technology
Volume10
Issue number7
DOIs
Publication statusPublished - 01-07-2017

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Dichlorodiphenyldichloroethane
Tertiary Healthcare
Tertiary Care Centers
Type 2 Diabetes Mellitus
Drug Utilization
Pharmaceutical Preparations
Metformin
Hospital Medical Records Department
Biguanides
Drug Prescriptions
National Institutes of Health (U.S.)
International Classification of Diseases
Combination Drug Therapy
Observational Studies
Registries
Comorbidity
Diabetes Mellitus
Retrospective Studies
Public Health
Economics

All Science Journal Classification (ASJC) codes

  • Pharmacology, Toxicology and Pharmaceutics (miscellaneous)
  • Pharmacology (medical)

Cite this

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title = "Utilization pattern of anti-diabetic drugs in type 2 diabetes mellitus in tertiary care hospital",
abstract = "Background: Diabetes mellitus is a major public-health related problem. The increase in prevalence rates has led to an increase in the economic burden, worldwide. To manage the disease in a better way, Drug utilization research can be used as a strategy to justify the drug therapy. Aims: To study the drug prescribing pattern of anti-diabetic drugs in newly diagnosed type 2 DM patients. Materials and methods: A retrospective observational study was carried out in a tertiary care hospital. As per the study criteria, data was collected from medical records department (MRD) registry using ICD code E 11.9.Data was analysed using SPSS 20.0 and the DDD per 100 bed-days was calculated. Results: A total of 662 patients were newly diagnosed with type 2 DM. The mean age of study population was 52.5 ± 12.5 years and 427(64.5{\%}) patients were male. Hypertension was the most common comorbidity observed in 189 (28.5{\%}) patients. Among the anti-diabetic drugs, the utilization of insulin (0.088 DDDs per 100 bed-days in 2013 and 0.16 DDDs per 100 bed-days in 2014) was highest and among the oral anti-diabetic drugs the utilization pattern of metformin (0.058 DDDs per 100 bed-days in 2013 and 0.071 DDDs per 100 bed-days in 2014) was the highest in both 2013 and 2014. Conclusion: Biguanides (metformin) was highly prescribed anti -diabetic drug in both single and combination drug therapies. This study shows that the treatment pattern of type 2 DM patients is in accordance to the NICE (National Institute for Health and Clinical Excellence) guidelines.",
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Utilization pattern of anti-diabetic drugs in type 2 diabetes mellitus in tertiary care hospital. / Raphael, Merry; Vijayanarayana, K.; Thunga, Girish; Karthik Rao, N.; Sreedharan, N.

In: Research Journal of Pharmacy and Technology, Vol. 10, No. 7, 01.07.2017, p. 2063-2068.

Research output: Contribution to journalArticle

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AU - Raphael, Merry

AU - Vijayanarayana, K.

AU - Thunga, Girish

AU - Karthik Rao, N.

AU - Sreedharan, N.

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N2 - Background: Diabetes mellitus is a major public-health related problem. The increase in prevalence rates has led to an increase in the economic burden, worldwide. To manage the disease in a better way, Drug utilization research can be used as a strategy to justify the drug therapy. Aims: To study the drug prescribing pattern of anti-diabetic drugs in newly diagnosed type 2 DM patients. Materials and methods: A retrospective observational study was carried out in a tertiary care hospital. As per the study criteria, data was collected from medical records department (MRD) registry using ICD code E 11.9.Data was analysed using SPSS 20.0 and the DDD per 100 bed-days was calculated. Results: A total of 662 patients were newly diagnosed with type 2 DM. The mean age of study population was 52.5 ± 12.5 years and 427(64.5%) patients were male. Hypertension was the most common comorbidity observed in 189 (28.5%) patients. Among the anti-diabetic drugs, the utilization of insulin (0.088 DDDs per 100 bed-days in 2013 and 0.16 DDDs per 100 bed-days in 2014) was highest and among the oral anti-diabetic drugs the utilization pattern of metformin (0.058 DDDs per 100 bed-days in 2013 and 0.071 DDDs per 100 bed-days in 2014) was the highest in both 2013 and 2014. Conclusion: Biguanides (metformin) was highly prescribed anti -diabetic drug in both single and combination drug therapies. This study shows that the treatment pattern of type 2 DM patients is in accordance to the NICE (National Institute for Health and Clinical Excellence) guidelines.

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