Zidovudine-induced reversible pure red cell aplasia

Anuja Balakrishnan, Rohith Valsalan, Shubha Sheshadri, Vinay R. Pandit, Vikas Medep, Ravindra Kumar Agrawal

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Abstract

Hematological abnormalities are frequent among human immunodeficiency virus (HIV)-infected patients and may be directly attributable to the virus or may be caused by opportunistic infections, neoplasms or drugs that cause bone marrow suppression or hemolysis. Pure red cell aplasia (PRCA) is an uncommon hematological disorder that causes anemia. We report a 37-year-old male with HIV infection who developed PRCA 6 weeks after commencing Zidovudine and recovered following cessation of the drug. This is the first case of Zidovudine-induced PRCA reported from the Indian subcontinent.

Original languageEnglish
Pages (from-to)189-191
Number of pages3
JournalIndian Journal of Pharmacology
Volume42
Issue number3
DOIs
Publication statusPublished - 01-05-2010

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All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmacology (medical)

Cite this

Balakrishnan, A., Valsalan, R., Sheshadri, S., Pandit, V. R., Medep, V., & Agrawal, R. K. (2010). Zidovudine-induced reversible pure red cell aplasia. Indian Journal of Pharmacology, 42(3), 189-191. https://doi.org/10.4103/0253-7613.66845