TY - JOUR
T1 - Zidovudine-induced reversible pure red cell aplasia
AU - Balakrishnan, Anuja
AU - Valsalan, Rohith
AU - Sheshadri, Shubha
AU - Pandit, Vinay R.
AU - Medep, Vikas
AU - Agrawal, Ravindra Kumar
PY - 2010/5/1
Y1 - 2010/5/1
N2 - Hematological abnormalities are frequent among human immunodeficiency virus (HIV)-infected patients and may be directly attributable to the virus or may be caused by opportunistic infections, neoplasms or drugs that cause bone marrow suppression or hemolysis. Pure red cell aplasia (PRCA) is an uncommon hematological disorder that causes anemia. We report a 37-year-old male with HIV infection who developed PRCA 6 weeks after commencing Zidovudine and recovered following cessation of the drug. This is the first case of Zidovudine-induced PRCA reported from the Indian subcontinent.
AB - Hematological abnormalities are frequent among human immunodeficiency virus (HIV)-infected patients and may be directly attributable to the virus or may be caused by opportunistic infections, neoplasms or drugs that cause bone marrow suppression or hemolysis. Pure red cell aplasia (PRCA) is an uncommon hematological disorder that causes anemia. We report a 37-year-old male with HIV infection who developed PRCA 6 weeks after commencing Zidovudine and recovered following cessation of the drug. This is the first case of Zidovudine-induced PRCA reported from the Indian subcontinent.
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U2 - 10.4103/0253-7613.66845
DO - 10.4103/0253-7613.66845
M3 - Article
AN - SCOPUS:77955446159
VL - 42
SP - 189
EP - 191
JO - Indian Journal of Pharmacology
JF - Indian Journal of Pharmacology
SN - 0253-7613
IS - 3
ER -